NCI Cancer Close-up Project (Images acquired by Assistant Prof Yongjian Liu)

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Images acquired by Assistant Professor Yongjian Liu have been chosen for this year’s NCI Cancer Close-up project.  They illustrate PET/CT imaging showing the tumor accumulation of DAPTA peptide functionalized, 64Cu doped gold nanocluster (64Cu-AuNCs-DAPTA) imaging CCR5 receptor in a triple negative breast cancer patient derived xenograph mouse model. The PET image was acquired at 24 h post intravenous injection.

2017 CMMN Pedal the Cause Team

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Dr. Achilefu would like to announce the formation of a 2017 CMMN Pedal the Cause team in support of the Cancer Frontier Fund. This research fund was established in 2009 by Alvin J. Siteman, an emeritus Washington University trustee, chairman of Site Oil Company and president of Flash Oil Company. Since the fund’s inception, 134 awards for a total of $21.7 million have been granted to Washington University faculty focused on cancer research.

100% of Pedal the Cause proceeds stay in St. Louis and go directly to the Cancer Frontier Fund, which supports cancer research at Washington University (WU) and St. Louis Children’s Hospital. Awards granted to WU faculty are managed by Siteman Cancer Center (SCC), a major contributor to CMMN. Participation by CMMN members shows our appreciation to SCC and demonstrates our commitment to both CMMN research and the community effort that raises local cancer research funds.

Team members may participate as riders, spinners or “virtual” riders (simply contribute to the cause). As a participant at the minimum levels, per the Request for Applications, qualifying faculty members may apply for cancer research funding (through the Siteman Investment Program) in one or both of two cycles in the year you participate. Faculty, students, staff and families are more than welcome to join the team.

Registration opens in March of 2017. More details to come. Information on the 2016 event can be found here: https://stlouis.pedalthecause.org/how_it_works.jsp

Please reply and indicate your interest in participating as a rider or virtual rider, as we build our team and ready ourselves for a productive year in 2017!

Funding Opportunity: Innovative Research in Cancer Nanotechnology (IRCN) (U01)

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Agency: Department of Health and Human Services, NIH, NCI

Mechanism: Innovative Research in Cancer Nanotechnology (IRCN) (U01)

FOA Number: PAR-14-285

Grant Term and Amount: 5 years, $450,000 in direct costs per year

Letter of Intent: Not applicable

Application deadline: October 15, 2016

Project Criteria:

This Funding Opportunity Announcement (FOA) invites applications for the development of innovative research projects in cancer nanotechnology. This initiative, to be known as Innovative Research in Cancer Nanotechnology (IRCN), is an integral component of a broader program – the NCI Alliance for Nanotechnology in Cancer (The Alliance) (https://nano.cancer.gov). IRCN awards are designed to enable multi-disciplinary research and transformative discoveries in cancer biology and/or oncology through the use of nanotechnology. Proposed projects should address major barriers in cancer biology and/or oncology using nanotechnology and should emphasize fundamental understanding of nanomaterial interactions with biological systems and/or mechanisms of their in vivo delivery.

NCI will hold a pre-application informational webinar for this FOA. Date, time, and other details will be posted at https://nano.cancer.gov.

More information: https://grants.nih.gov/grants/guide/pa-files/PAR-14-285.html#_3._Additional_Information

CMMN Positions Available

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Position: Postdoctoral Research Associates in Synthetic Organic Chemist

Position available immediately for a highly motivated postdoctoral fellowship in the area of synthetic organic chemistry. The candidate will synthesize new drug molecules, molecular probes, and peptides for cancer therapy, imaging, and monitoring treatment response. The candidate is expected to develop and implement synthetic strategies for the synthesis of complex organic molecules and functionalization of nanoparticles. Knowledge of diverse synthetic pathways, reaction mechanisms, modern analytical techniques, and interest in applying organic chemistry to solving biological problems is preferred. The candidate will work in a multidisciplinary research platform that includes chemists, biologists, physicists, molecular imaging scientists, and clinicians. The initial appointment is for one year, but can be renewed up to three years based on performance and the availability of fund. If interested, candidates are offered the opportunity to develop skills for an independent career in academia or industry. Excellent writing and communication skills are necessary for this position.

Minimum Qualifications: Ph.D. in Organic Chemistry or equivalent, with less than three years since receiving the degree.

Principal Investigator: Candidate will report Samuel Achilefu, Ph.D.; Professor & Director, Optical Radiology Lab, Department of Radiology, Washington University School of Medicine, St. Louis, Missouri.

 

Position: Synthetic Organic Chemist 

Position available immediately for a synthetic organic chemist. The Candidate will synthesize and purify organic molecules, fluorescent dyes, peptides, and bioconjugates. The successful candidate is expected to develop standard synthetic protocols, organize data, and report findings to the principal investigator. Optical Radiology Lab, where the candidate will work, offers a unique opportunity for interaction with a diverse group of faculty members, staff scientists, and students. Because this position requires the ability of the candidate to handle multiple projects, highly motivated and energetic candidates are encouraged to apply.

Minimum education & experience: MS in Chemistry or BS with three years of experience.

Principal Investigator: Candidate will report Samuel Achilefu, Ph.D.; Professor & Director, Optical Radiology Lab, Department of Radiology, Washington University School of Medicine, St. Louis, Missouri.

 

Position: Analytical Chemist 

Position available immediately for an analytical chemist. The candidate is expected to analyze organic molecules and conjugates using standard analytical methods (LCMS, NMR, spectroscopy) and maintain analytical instrumentation, including HPLC, LCMS, spectrophotometers. Purification of compounds and quantitative analysis are essential components of the job function. The successful candidate will participate in group meetings and prepare reports. Optical Radiology Lab, where the candidate will work, offers a unique opportunity for interaction with a diverse group of faculty members, staff scientists, and students. Because this position requires the ability of the candidate to handle multiple projects, highly motivated and energetic candidates are encouraged.

Minimum education & experience: MS in Chemistry/Biochemistry/Materials Science or BS with three years of experience.

Principal Investigator: Candidate will report Samuel Achilefu, Ph.D.; Professor & Director, Optical Radiology Lab, Department of Radiology, Washington University School of Medicine, St. Louis, Missouri.